Chicago White Sox vs Cleveland Guardians

MLB

White Sox

6-6

3-6

Final

Guardians

7-5

Progressive Field

TV: MLB.TV

Team	1	2	3	4	5	6	7	8	9	R
CHW	0	0	0	1	0	0	2	0	0	3
CLE	0	0	2	0	1	1	2	0	X	6

Who won: Guardians 6-3

The Cleveland Guardians beat the Chicago White Sox 6-3 on Thursday, April 21, 2022 at Progressive Field. The Guardians win the series 3-0. The Guardians outscored the White Sox 2-0 in the 3rd inning. Franmil Reyes went 2-for-3 with a home run and 2 RBI for the Guardians. Luis Robert Jr. went 2-for-4 for the White Sox.

Recap · Apr 21

Naylor, Plesac lead Guardians to sweep of White Sox 6-3

Josh Naylor had two hits and two RBI, continuing his comeback from a devastating leg injury and helping the Cleveland Guardians complete a series sweep of the Chicago White Sox with a 6-3 victory on Thursday.

What it means

Season series: CLE wins series 3-0.
White Sox 2-4 on the road; Guardians 3-3 at home.

Latest headlines

ESPN · 4h ago

Rain postpones Game 4 of ALCS to Saturday; Rays, Guardians to play Game 5 on Sunday

ESPN · 5h ago

Lineups, live updates for Rays-Guardians ALCS Game 4

ESPN · 15h ago

Guardians to open with Armstrong; Rays start Martinez in ALCS Game 4

ESPN · 18h ago

Petey Halpin launches homer, bat to put Guardians past Rays in ALCS Game 3

Recap · 23h ago

Halpin’s go-ahead homer flips Game 3 as Guardians beat Rays 3-2 for 2-1 AL Championship Series lead

Preview · 23h ago

Guardians lead Rays 2-1 ahead of ALCS Game 4

ESPN · 1d ago

Guardians hold off Rays to take 2-1 lead in ALCS

ESPN · 2d ago

MLB 2026: How Jose Ramirez's energy is fueling Guardians' run

Injuries and inactives

White Sox2nd in AL Cent

Joey Bart C
Hand, Fracture, left
10-Day-IL
Ky Bush SP
Elbow, Surgery, left
60-Day-IL
Luis Castillo SP
Shoulder, Pinched Nerve, right
15-Day-IL
Prelander Berroa RP
Elbow, Surgery, right
60-Day-IL
Tanner Murray LF
Shoulder, Surgery, left
60-Day-IL

Guardians1st in AL Cent

Andrew Walters RP
Elbow, Surgery, right
Out
Colin Holderman RP
Wrist, Surgery, right
15-Day-IL
Rhys Hoskins 1B
Back, Inflammation
10-Day-IL

Probable starters

White Sox2nd in AL Cent

Dylan Cease SP

Probable starter · 14-8, 2.20 ERA, 227 K, 1.11 WHIP

Lineup

1Tim AndersonSS
2Luis Robert Jr.CF
3Leury Garcia2B
4Jose Abreu1B
5Yasmani GrandalC
6Eloy JimenezDH
7Gavin SheetsRF
8Jake Burger3B
9Adam HaseleyCF

Guardians1st in AL Cent

Zach Plesac SP

Probable starter · 3-12, 4.31 ERA, 100 K, 1.32 WHIP

Lineup

1Steven KwanLF
2Amed RosarioDH
3Jose Ramirez3B
4Franmil ReyesRF
5Josh Naylor1B
6Ernie Clement2B
7Andres GimenezSS
8Oscar MercadoRF
9Austin HedgesC

The series

CLE wins series 3-0

Last meeting: Guardians 2, White Sox 1 (Apr 20)

Chirp's angle

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Game info

Venue: Progressive Field, Cleveland, Ohio · Attendance 8,345
Officials: Chad Fairchild (Home Plate Umpire), Shane Livensparger (First Base Umpire), Laz Diaz (Second Base Umpire), Brian O'Nora (Third Base Umpire)