Chicago White Sox vs Cleveland Guardians, Doubleheader Game 1 Makeup from April 19
| Team | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | R |
|---|---|---|---|---|---|---|---|---|---|---|
 CHW | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 |
 CLE | 1 | 9 | 0 | 0 | 0 | 0 | 0 | 1 | X | 11 |
Who won: Guardians 11-1
The Cleveland Guardians beat the Chicago White Sox 11-1 in Doubleheader Game 1 Makeup from April 19 on Wednesday, April 20, 2022 at Progressive Field. The Guardians win the series 3-0. The Guardians outscored the White Sox 9-0 in the 2nd inning. Jose Ramirez went 1-for-4 with a home run and 4 RBI for the Guardians.
