NFL · Head to head
Bills vs 49ers
The Bills won their only meeting with the 49ers, by an average of 25 points. Last meeting: Bills 35, 49ers 10 on Nov 30, 2024.
BUF record
1-0
Last 5
1-0
BUF points
35.0
SF points
10.0
Every meeting
| Date | Result | Top performers |
|---|---|---|
| Nov 30, 2024vs SF | W 35-10 |
Bills players in this matchup
49ers players in this matchup