San Diego Padres vs Houston Astros
| Team | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | R |
|---|---|---|---|---|---|---|---|---|---|---|
 SD | 0 | 1 | 0 | 1 | 0 | 0 | 2 | 0 | 0 | 4 |
 HOU | 0 | 3 | 1 | 1 | 0 | 0 | 0 | 1 | X | 6 |
Who won: Astros 6-4
The Houston Astros beat the San Diego Padres 6-4 on Friday, April 18, 2025 at Daikin Park. The Astros win the series 2-1. The Astros outscored the Padres 3-1 in the 2nd inning. Cam Smith went 2-for-4 with 2 home runs and 4 RBI for the Astros. Luis Arraez went 3-for-5 with a home run and 2 RBI for the Padres.
