49ers vs Chargers Score and Box Score | ChirpSan Francisco 49ers vs Los Angeles Chargers score
| Passing | C/ATT | YDS | AVG | TD | INT | SACKS | RTG |
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| DJ Uiagalelei | 7/15 | 80 | 5.3 | 1 | 0 | 1-1 | 85.4 |
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| Trey Lance | 10/16 | 73 | 4.6 | 0 | 0 | 0-0 | 73.2 |
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| Justin Herbert |
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| Rushing | CAR | YDS | AVG | TD | LONG |
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| Trey Lance | 2 | 42 | 21.0 | 0 | 37 |
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| Greg Desrosiers Jr. | 4 | 21 | 5.3 | 0 | 8 |
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| Jaret Patterson | 3 | 7 | 2.3 | 0 | 7 |
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| Kimani Vidal | 4 | 6 | 1.5 | 0 | 3 |
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| Keaton Mitchell | 3 | -1 | -0.3 | 0 | 1 |
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| Amar Johnson | 2 | -1 | -0.5 | 0 | 0 |
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| Omarion Hampton | 1 | -1 | -1.0 | 0 | -1 |
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| DJ Uiagalelei | 1 | -5 | -5.0 | 0 | -5 |
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| Receiving | REC | YDS | AVG | TD | LONG | TGTS |
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| Jerand Bradley | 1 | 28 | 28.0 | 1 | 28 | 1 |
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| Oronde Gadsden | 2 | 24 | 12.0 | 0 | 16 | 3 |
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| Devonte Ross | 2 | 24 | 12.0 | 0 | 16 | 3 |
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| Dalevon Campbell | 2 | 16 | 8.0 | 0 | 10 | 4 |
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| KeAndre Lambert-Smith | 2 | 14 | 7.0 | 0 | 8 | 4 |
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| Keaton Mitchell | 1 | 11 | 11.0 | 0 | 11 | 1 |
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| Kimani Vidal | 2 | 10 | 5.0 | 0 | 5 | 2 |
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| Charlie Kolar | 1 | 9 | 9.0 | 0 | 9 | 1 |
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| Brenen Thompson | 1 | 9 | 9.0 | 0 | 9 | 2 |
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| Johnny Pascuzzi | 1 | 7 | 7.0 | 0 | 7 | 2 |
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| Derius Davis | 1 | 5 | 5.0 | 0 | 5 | 3 |
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| Scott Matlock | 2 | 5 | 2.5 | 0 | 3 | 2 |
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| Sincere Brown | 0 | 0 | 0.0 | 0 | 0 | 1 |
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| Ladd McConkey | 0 | 0 | 0.0 | 0 | 0 | 1 |
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| Greg Desrosiers Jr. | 0 | 0 | 0.0 | 0 | 0 | 1 |
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| Amar Johnson | 0 | 0 | 0.0 | 0 | 0 | 1 |
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| JaQuae Jackson | 0 | 0 | 0.0 | 0 | 0 | 1 |
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| Fumbles | FUM | LOST | REC |
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| Devonte Ross | 1 | 1 | 0 |
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| Defensive | TOT | SOLO | SACKS | TFL | PD | QB HTS | TD |
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| Lander Barton | 6 | 3 | 0 | 0 | 0 | 0 | 0 |
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| Avery Smith | 6 | 2 | 0 | 0 | 0 | 0 | 0 |
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| Emany Johnson | 4 | 3 | 0 | 0 | 1 | 0 | 0 |
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| Rodney Shelley | 4 | 3 | 0 | 0 | 2 | 0 | 0 |
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| Nikko Reed | 4 | 1 | 0 | 0 | 0 | 0 | 0 |
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| Tony Jefferson | 3 | 3 | 0 | 0 | 0 | 0 | 0 |
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| Marlowe Wax | 3 | 2 | 0 | 0 | 0 | 0 | 0 |
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| Genesis Smith | 3 | 2 | 0 | 0 | 0 | 0 | 0 |
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| Jacobian Guillory II | 3 | 1 | 0 | 0 | 0 | 0 | 0 |
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| Justin Eboigbe | 3 | 1 | 0 | 0 | 0 | 0 | 0 |
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| Andre Carter II | 3 | 1 | 0 | 0 | 0 | 0 | 0 |
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| Myles Purchase | 3 | 1 | 0 | 0 | 0 | 0 | 0 |
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| Kendall Williamson | 2 | 2 | 0 | 0 | 1 | 0 | 0 |
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| Nick Barrett | 2 | 2 | 0 | 0 | 0 | 0 | 0 |
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| Deane Leonard | 2 | 2 | 0 | 0 | 0 | 0 | 0 |
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| Del'Shawn Phillips | 2 | 1 | 0 | 0 | 0 | 0 | 0 |
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| Garmon Randolph | 2 | 1 | 0 | 0 | 0 | 0 | 0 |
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| Jahmeer Carter | 2 | 1 | 0 | 0 | 0 | 0 | 0 |
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| TeRah Edwards | 2 | 1 | 0 | 0 | 0 | 0 | 0 |
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| Denzel Perryman | 2 | 0 | 0 | 0 | 0 | 0 | 0 |
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| Devin Grant | 2 | 0 | 0 | 0 | 1 | 0 | 0 |
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| Daiyan Henley | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
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| Cam Hart | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
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| RJ Mickens | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
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| Kimani Vidal | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
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| Tuli Tuipulotu | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
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| Greg Desrosiers Jr. | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
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| Elijah Molden | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
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| Junior Colson | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
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| Isas Waxter | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
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| Nadame Tucker | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
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| Interceptions | INT | YDS | TD |
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| Junior Colson | 1 | 16 | 1 |
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| Devin Grant | 1 | 0 | 0 |
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| KickReturns | NO | YDS | AVG | LONG | TD |
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| Amar Johnson | 2 | 52 | 26.0 | 30 | 0 |
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| Kimani Vidal | 1 | 27 | 27.0 | 27 | 0 |
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| Jaret Patterson | 1 | 25 | 25.0 | 25 | 0 |
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| JaQuae Jackson | 1 | 19 | 19.0 | 19 | 0 |
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| Devonte Ross | 1 | 14 | 14.0 | 14 | 0 |
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| PuntReturns | NO | YDS | AVG | LONG | TD |
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| KeAndre Lambert-Smith | 2 | 15 | 7.5 | 11 | 0 |
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| Devonte Ross | 1 | 7 | 7.0 | 7 | 0 |
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| Kicking | FG | PCT | LONG | XP | PTS |
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| Cameron Dicker | 1/1 | 100.0 | 21 | 0/1 | 3 |
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| Punting | NO | YDS | AVG | TB | In 20 | LONG |
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| JK Scott | 8 | 381 | 47.6 | 0 | 4 | 62 |
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